Biology is beautiful!

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Explorers in the wilderness of cancer biology

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Patrick Hsu @pdhsu ·

14 Nov

Today we report Evo, a generalist foundation model for biology, on the cover of @ScienceMagazine. Trained on billions of DNA nucleotides, Evo was designed to capture two key aspects of biology: the multi-modality of the central dogma and the multi-scale nature of evolution.

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Matthia Karreman @ma_karreman ·

7 Oct

How do T cells reach melanoma brain tumors?

Using in vivo microscopy, we discovered a new route for T cells to enter the brain via distinct peri-tumoral venous vessels.

Our newest paper is now online @ImmunityCP.
https://authors.elsevier.com/sd/article/S1074-7613(24)00447-3

A 🧵👇

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Nature Medicine @naturemedicine ·

8 Oct

Using data from a cohort of 402 #LungAdenocarcinoma patients and from multiple independent cohorts, DNA #Methylation signatures were evaluated to build and validate an accurate model predicting #BrainMetastasis development. @JeffreyZuccato @gelarehzadeh

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S.Zhang Lab @szhang_lab ·

6 Oct

Inspiring… what important questions are we working on 😅

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